Ausschreibung Kurse und Praktika

Opportunity to conduct master’s thesis/rotation at The Broad Institute of MIT and Harvard

Broad Institute is the world’s leading biomedical research institute dedicated to the mission of using the power of genomics to transform the understanding and treatment of disease. The Manguso Lab at the Broad Institute has created the Tumor Immunotherapy
Discovery Engine (TIDE), a project devoted to applying functional genomics for in vivo discovery of novel cancer immunotherapy targets. The multidisciplinary team of research scientists, computational biologists, and research associates uses cutting edge techniques including but not limited to high-throughput genetic screening, CRISPR/Cas9 genome editing, preclinical murine models for immunotherapy, and single-cell RNA sequencing to improve our
understanding of tumoral mechanisms of immune evasion.
We seek a highly motivated masters students to join our team at the Broad Institute for minimum of 7-9 months. This role will work closely with senior investigators, and requires the ability to communicate effectively, work well in a team setting, and a strong desire to learn new methods. Your work will be central to several major research projects, and co-authorship on high-impact publications is strongly supported. The research will require you to be adaptable and able to work in a fast-paced and demanding environment. Learning new techniques in the lab or from other labs to increase expertise will be encouraged. Candidates should have
excellent communication skills, be highly organized, and comfortable with new technology. This position will provide an outstanding experience for a career in science, medicine or biotechnology.


Conducts experiments and/or assays following standard or detailed protocol; identifies and documents variations that may affect the validity of the experiment.
Works with mice for in vivo experiments to assess tumor growth.
Data collection and analysis. Performs quality control, monitors data for accuracy, and discusses results within agreed upon timelines with supervisor.
Validate and conduct studies based upon standard experimental protocols within the agreed upon timelines with supervisor/technical manager. Ensure functionality and maintenance of instrumentation and/or reagent stocks.
Demonstrated success in coordinating and/or conducting multiple, concurrent assignments or a multi-faceted project.
Advanced computer skills, ability to develop technical documents and presentations.
Willingness and ability to work flexible shifts (evening/weekend/holiday).
Participates in internal meetings to share results and plan experiments.


Bachelor’s degree in Biology or a related field with experience working in a research lab required. Currently enrolled in master’s program in Biology.
Detail oriented and able to think creatively to solve problems.
Proficient with molecular biology laboratory techniques.
Experience with mammalian cell and tissue culture techniques is strongly preferred.
Strong interpersonal, communication and organizational skills, including the ability to handle a
variety of tasks in a fast-paced environment.
High level of initiative and motivation; ability to work independently and with a team.


Please supply CV and transcript of records.